Moderation and mediation of an effective HIV risk-reduction intervention for South African adolescents
- PMID: 22618963
- PMCID: PMC4349630
- DOI: 10.1007/s12160-012-9375-4
Moderation and mediation of an effective HIV risk-reduction intervention for South African adolescents
Abstract
Background: "Let Us Protect Our Future" is a sexual risk-reduction intervention for sixth-grade adolescents in South Africa. Tested in a cluster-randomized controlled trial, the intervention significantly reduced self-reported intercourse and unprotected intercourse during a 12-month follow-up period.
Purpose: The present analyses were conducted to identify moderators of the intervention's efficacy as well as, which theory-based variables mediated the intervention's effects.
Methods: Intervention efficacy over the 3-, 6-, and 12-month follow-up was tested using generalized estimating equation models.
Results: Living with their father in the home, parental strictness, and religiosity moderated the efficacy of the intervention in reducing unprotected intercourse. Self-efficacy to avoid risky situations and expected parental disapproval of their having intercourse, derived from Social Cognitive Theory, significantly mediated the intervention's effect on abstinence.
Conclusions: This is the first study to demonstrate that Social Cognitive variables mediate the efficacy of a sexual risk-reduction intervention among South African adolescents.
Comment in
-
International collaborations and multidisciplinary approaches in high-quality behavioral medicine research: a comment on O'Leary et al.Ann Behav Med. 2012 Oct;44(2):149-50. doi: 10.1007/s12160-012-9391-4. Ann Behav Med. 2012. PMID: 22752979 No abstract available.
Similar articles
-
Long-term mediation of a sexual risk-reduction intervention for South African adolescents.Health Psychol. 2023 Nov;42(11):810-821. doi: 10.1037/hea0001325. Health Psychol. 2023. PMID: 37883037
-
Mediation of an efficacious HIV risk reduction intervention for South African men.AIDS Behav. 2015 Oct;19(10):1842-9. doi: 10.1007/s10461-015-1042-x. AIDS Behav. 2015. PMID: 25969177
-
HIV/STI risk-reduction intervention efficacy with South African adolescents over 54 months.Health Psychol. 2015 Jun;34(6):610-21. doi: 10.1037/hea0000140. Epub 2014 Aug 11. Health Psychol. 2015. PMID: 25110841 Free PMC article. Clinical Trial.
-
School-based randomized controlled trial of an HIV/STD risk-reduction intervention for South African adolescents.Arch Pediatr Adolesc Med. 2010 Oct;164(10):923-9. doi: 10.1001/archpediatrics.2010.176. Arch Pediatr Adolesc Med. 2010. PMID: 20921349 Free PMC article. Clinical Trial.
-
HIV/AIDS in South Africa: a review of sexual behavior among adolescents.Adolescence. 2005 Spring;40(157):171-81. Adolescence. 2005. PMID: 15861624 Review.
Cited by
-
Evidence and gap map report: Social and Behavior Change Communication (SBCC) interventions for strengthening HIV prevention and research among adolescent girls and young women (AGYW) in low- and middle-income countries (LMICs).Campbell Syst Rev. 2023 Jan 10;19(1):e1297. doi: 10.1002/cl2.1297. eCollection 2023 Mar. Campbell Syst Rev. 2023. PMID: 36911864 Free PMC article.
-
Alcohol outlet density and related use in an urban Black population in Philadelphia public housing communities.Health Place. 2015 Jan;31:31-8. doi: 10.1016/j.healthplace.2014.10.007. Epub 2014 Nov 15. Health Place. 2015. PMID: 25463915 Free PMC article.
-
Sex and sexual orientation disparities in adverse childhood experiences and early age at sexual debut in the United States: results from a nationally representative sample.Child Abuse Negl. 2015 Aug;46:89-102. doi: 10.1016/j.chiabu.2015.02.019. Epub 2015 Mar 21. Child Abuse Negl. 2015. PMID: 25804435 Free PMC article.
-
Mediating Pathways in Faith-Based Sexual Risk-Reduction for African American Adolescents: Insights from a Church-Based Randomized Controlled Trial.J Racial Ethn Health Disparities. 2025 May 7. doi: 10.1007/s40615-025-02446-1. Online ahead of print. J Racial Ethn Health Disparities. 2025. PMID: 40332746
-
A Systematic Review of Randomized Controlled Trials of School Based Interventions on Sexual Risk Behaviors and Sexually Transmitted Infections Among Young Adolescents in Sub-Saharan Africa.AIDS Behav. 2021 Nov;25(11):3669-3686. doi: 10.1007/s10461-021-03242-8. Epub 2021 Mar 27. AIDS Behav. 2021. PMID: 33772695 Free PMC article.
References
-
- UNAIDS AIDS epidemic update: December 2009. Geneva: Joint United Nations Programme on HIV/AIDS (UNAIDS) and World Health Organization (WHO) 2010.
-
- South African Department of Health National HIV and syphilis antenatal sero-prevalence survey in South Africa 2005. 2006 Available from: http://www.doh.gov.za/docs/reports-f.html.
-
- Dorrington RE, Johnson LF, Bradshaw D, Daniel T. The demographic impact of HIV/AIDS in South Africa: national and provincial indicators for 2006. Centre for Actuarial Research, South African Medical Research Council, and Actuarial Society of South Africa; Cape Town: 2006. Available from: http://www.mrc.ac.za/bod/DemographicImpactHIVIndicators.pdf.
-
- Richter LM. Young people in South Africa: the status of youth report 2003. Human Sciences Research Council; Pretoria: 2005.