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Comment
. 2012 May 23;4(135):135le3; author reply 135lr3.
doi: 10.1126/scitranslmed.3004162.

Comment on "the predictive capacity of personal genome sequencing"

Colin B Begg, Malcolm C Pike
Comment

Comment on "the predictive capacity of personal genome sequencing"

Colin B Begg et al. Sci Transl Med. .
No abstract available

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Figures

Figure
Figure. Standardized Lognormal Risk Distributions
. Each curve represents the population distribution of risks under the assumption that the distribution is lognormal, where the value of 1 on the horizontal axis represents the population mean risk. Thus, as the SIR increases, the distribution becomes more and more spread out, with the large preponderance of the population experiencing risks much lower that the average population risk, and a small proportion having increasingly larger risks.
See this image and copyright information in PMC

Comment on

  • The predictive capacity of personal genome sequencing.
    Roberts NJ, Vogelstein JT, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE. Roberts NJ, et al. Sci Transl Med. 2012 May 9;4(133):133ra58. doi: 10.1126/scitranslmed.3003380. Epub 2012 Apr 2. Sci Transl Med. 2012. PMID: 22472521 Free PMC article.

References

    1. Roberts NJ, Vogelstein JT, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE. The predictive capacity of personal genome sequencing. Sci Transl Med. 2012 Apr 2; doi: 10.1126/scitranslmed.3003380. - DOI - PMC - PubMed
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