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Randomized Controlled Trial
. 2013 Sep-Oct;12(5):343-8.
doi: 10.1177/1545109712446177. Epub 2012 May 24.

Enhancing HIV medication adherence in India

Deborah Jones  1 , Aman Sharma, Mahendra Kumar, Drenna Waldrop-Valverde, Ritu Nehra, Szonja Vamos, Ryan Cook, Stephen M Weiss
Affiliations
Randomized Controlled Trial

Enhancing HIV medication adherence in India

Deborah Jones et al. J Int Assoc Provid AIDS Care. 2013 Sep-Oct.

Abstract

Background: This pilot study evaluated an intervention designed to enhance adherence among those new to antiretroviral therapy.

Methods: Participants (n = 80) were recruited from a hospital clinic in Chandigarh, India, and randomized to a 3-month group intervention or individual enhanced standard of care followed by crossover of condition and assessed over 6 months. Adherence was measured by prescription refill, pill count, and self-report.

Results: At baseline, 56% of group condition (immediate intervention) and 54% of individual condition (delayed intervention) participants were nonadherent by pill count and 23% of group and 26% of individual condition participants self-reported skipping medication at least once over the last 3 months. From the postintervention to long-term follow-up, adherence in the group condition (immediate intervention) improved in comparison with adherence in the individual condition (delayed intervention; χ(2) = 5.67, P = .02).

Conclusions: Results support the use of interventions early in treatment to provide information and social support to establish long-term healthy adherence behaviors.

Keywords: India; adherence; assessment; behavior; intervention.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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References

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