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. 2012 May;16(3):349-57.
doi: 10.4103/2230-8210.95662.

Osteoanabolics

Vishal Gupta  1 , Mitul Abhaykumar Shah, Sagar Kirtibhai Shah, Jinen Mukeshbhai Shah
Affiliations

Osteoanabolics

Vishal Gupta et al. Indian J Endocrinol Metab. 2012 May.

Abstract

Osteoporosis is characterized by reduced bone mass, impaired bone quality, and a propensity to fracture. An "osteoanabolic" should be referred to any therapy that helps increase bone mass. Bone mass represents 80% of bone mechanical strength. A low bone mass therefore provides the strongest association of future risk of fracture. This review aims to discuss all available and future therapies that attempt to increase bone mass be it organic or inorganic.

Keywords: Bone remodeling; osteo-anabolics; osteoporosis; teriparatide.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Bone remodelling: m-CSF (macrophage colony stimulating factor) and RANKL (receptor activator of NF-kappaB ligand)
Figure 2
Figure 2
Possible future therapeutic targets for drugs acting via WNT signaling pathway[59]
See this image and copyright information in PMC

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