Oral manifestations in growth hormone disorders
- PMID: 22629503
- PMCID: PMC3354844
- DOI: 10.4103/2230-8210.95678
Oral manifestations in growth hormone disorders
Abstract
Growth hormone is of vital importance for normal growth and development. Individuals with growth hormone deficiency develop pituitary dwarfism with disproportionate delayed growth of skull and facial skeleton giving them a small facial appearance for their age. Both hyper and hypopituitarism have a marked effect on development of oro-facial structures including eruption and shedding patterns of teeth, thus giving an opportunity to treating dental professionals to first see the signs and symptoms of these growth disorders and correctly diagnose the serious underlying disease.
Keywords: Acromegaly; dwarfism; gigantism; growth hormone.
Conflict of interest statement
References
-
- Shafer GW, Hine MK, Levy BM, editors. A Textbook of Oral Pathology. 4th ed. India: Harcourt Brace Asia Inc; 1994. Oral aspects of metabolic disease; pp. 654–7.
-
- Neville B, Damm DD, Allen MC, editors. 3rd ed. India: Elsevier Inc; 2010. Oral and maxillofacial pathology; pp. 831–3.
-
- Kosowicz J, Rzymski K. Abnormalities of tooth development in pituitary dwarfism. Oral Surg Oral Med Oral Pathol. 1977;44:853–63. - PubMed
-
- Sarnat H, Kaplan I, Pertzelan A, Laron Z. Comparison of dental findings in patients with isolated growth hormone deficiency treated with human growth hormone (hGH) and in untreated patients with Laron-type dwarfism. Oral Surg Oral Med Oral Pathol. 1988;66:581–6. - PubMed
-
- Bigeard L, Sommermater J. Dental delay and microdontia in children with somatotropin hormone deficiency. J Biol Buccale. 1991;19:291–6. - PubMed