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Comment
. 2012 May 24;74(4):597-9.
doi: 10.1016/j.neuron.2012.05.002.

Complement-mediated microglial clearance of developing retinal ganglion cell axons

Carolyn M Tyler  1 , Lisa M Boulanger
Affiliations
Comment

Complement-mediated microglial clearance of developing retinal ganglion cell axons

Carolyn M Tyler et al. Neuron. .

Abstract

In many parts of the developing vertebrate nervous system, axons are pruned to establish mature patterns of connectivity. In this issue of Neuron, Schafer et al. (2012) show that microglia may play a role in developmental axon pruning in the thalamus by engulfing presynaptic retinal ganglion cell terminals via a C3- and CR3-dependent mechanism.

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Figures

Figure 1
Figure 1
Microglia Phagocytose RGC Axon Material in a C3- and CR3-Dependent Manner
See this image and copyright information in PMC

Comment on

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