Comment
doi: 10.1016/j.neuron.2012.05.003.
In epilepsy, BAD is not really bad
Affiliations
- PMID: 22632717
- DOI: 10.1016/j.neuron.2012.05.003
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Comment
In epilepsy, BAD is not really bad
Neuron.
.
Free article
Abstract
In this issue of Neuron, Giménez-Cassina et al. (2012) show that fuel utilization by neuronal mitochondria, controlled by the Bcl-2 family member BAD, defines response to seizures. Control of K(ATP) channels by mitochondrial metabolism might be a target for antiepileptic therapies.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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BAD-dependent regulation of fuel metabolism and K(ATP) channel activity confers resistance to epileptic seizures.Neuron. 2012 May 24;74(4):719-30. doi: 10.1016/j.neuron.2012.03.032. Neuron. 2012. PMID: 22632729 Free PMC article.
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