IL-2: fine-tuning the germinal center reaction
- PMID: 22633457
- DOI: 10.1016/j.immuni.2012.05.005
IL-2: fine-tuning the germinal center reaction
Abstract
T follicular cells help B cells to drive germinal center formation. In this issue of Immunity, Ballesteros-Tato et al. (2012) demonstrate that high amounts of interleukin-2 inhibit production of this critical T effector subset.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation.Immunity. 2012 May 25;36(5):847-56. doi: 10.1016/j.immuni.2012.02.012. Epub 2012 Mar 29. Immunity. 2012. PMID: 22464171 Free PMC article.
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