[Diseases caused by diisocyanates. 2. Diisocyanate asthma]
[Article in
German]
- PMID: 226341
Item in Clipboard
[Diseases caused by diisocyanates. 2. Diisocyanate asthma]
[Article in
German]
Derm Beruf Umwelt.
1979.
Abstract
Diisocyanates are widely used as polymerizing agents in the production of polyurethanes. Exposure to high concentrations of toluene diisocyanate (TDI) causes the development of toxic-irritative symptoms in the respiratory tract. It has been observed that some workers, after repeated exposures and a latent period of months to years, develop asthmatic symptoms upon re-exposure to minute concentrations of diisocyanates. An immunological mechanism for this typical extrinsic asthma has not been adequately documented.
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