Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Sep;5(4):551-559.
doi: 10.2217/ahe.09.47.

Changes in immune function in asthma in the elderly

Sameer K Mathur, Sharmilee M Nyenhuis

Changes in immune function in asthma in the elderly

Sameer K Mathur et al. Aging health. 2009 Sep.

Abstract

Asthma is an inflammatory disorder of the airway. The airway inflammation of asthma is typically an allergic inflammation characterized by cells and mediators described as a "Th2" inflammatory response. There is a growing body of evidence describing changes in the function of immune cells upon aging, a phenomenon referred to as "immunosenescence". Several studies utilizing animal models and human subjects with asthma have begun to explore age-related effects on the airway inflammation in asthma. This review explores the existing data on the presence and effects of immunosenescence or age-related changes in immune function in asthma.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. NAEPP. NIH Publication No. 07-4051. National Institutes of Health: National Heart, Lung, and Blood Institute; 2007. Aug 28, Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma.. ** NIH workshop report that provides the latest guidelines for asthma diagnosis and management.

    1. Slavin RG. Asthma in the Elderly. Respiratory Digest. 2006;8(2):3–11.
    1. Moorman JE, Rudd RA, Johnson CA, King M, Minor P, Bailey C, et al. National Surveillance for Asthma- United States, 1980–2004. MMWR Surveillance Summaries. 2007;56(SS08):1–54. - PubMed
    1. Moorman JE, Mannino DM. Increasing US asthma mortality rates: Who is really dying? Journal of Asthma. 2001;38(1):65–71. - PubMed

    1. NAEPP. NIH Publication No. 96-3662. National Institutes of Health: National Heart, Lung, and Blood Institute; 1996. Considerations for Diagnosing and Managing Asthma in the Elderly.. * NIH workshop report that discusses the diagnostic and management concerns for an older asthma population, while highlighting several areas of deficient knowledge.

LinkOut - more resources