Review
doi: 10.1016/B978-0-12-394623-2.00006-8.
Energy expenditure: role of orexin
Affiliations
- PMID: 22640610
- PMCID: PMC4498671
- DOI: 10.1016/B978-0-12-394623-2.00006-8
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Review
Energy expenditure: role of orexin
Vitam Horm.
2012.
Abstract
The orexins/hypocretins are endogenous, modulatory and multifunctional neuropeptides with prominent influence on several physiological processes. The influence of orexins on energy expenditure is highlighted with focus on orexin action on individual components of energy expenditure. As orexin stabilizes and maintains normal states of arousal and the sleep/wake cycle, we also highlight orexin mediation of sleep and how sleep interacts with energy expenditure.
Copyright © 2012 Elsevier Inc. All rights reserved.
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References
-
- Alam MN, McGinty D, Szymusiak R. Neuronal discharge of preoptic/ anterior hypothalamic thermosensitive neurons: Relation to NREM sleep. Am J Physiol. 1995;269:R1240–R1249. - PubMed
-
- Alam MN, McGinty D, Szymusiak R. Preoptic/anterior hypothalamic neurons: Thermosensitivity in wakefulness and non rapid eye movement sleep. Brain Res. 1996;718:76–82. - PubMed
-
- Ammoun S, Holmqvist T, Shariatmadari R, Oonk HB, Detheux M, Parmentier M, Akerman KE, Kukkonen JP. Distinct recognition of OX1 and OX2 receptors by orexin peptides. J Pharmacol Exp Ther. 2003;305:507–514. - PubMed
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