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Case Reports
. 2012 May 29:4:27.
doi: 10.1186/1758-3284-4-27.

Metastatic rhabdomyosarcoma of the thyroid gland, a case report

Mohamed T Hafez  1 , Mohamed A Hegazy, Khaled Abd Elwahab, Mohammad Arafa, Islam Abdou, Basel Refky
Affiliations
Case Reports

Metastatic rhabdomyosarcoma of the thyroid gland, a case report

Mohamed T Hafez et al. Head Neck Oncol. .

Expression of concern in

  • Comment: Head and Neck Oncology.
    BioMed Central. BioMed Central. BMC Med. 2014 Feb 5;12:24. doi: 10.1186/1741-7015-12-24. BMC Med. 2014. PMID: 24499430 Free PMC article. Review.

Abstract

The thyroid gland is a known but an unusual site for metastatic tumors from various primary sites. Despite the fact that it is one of the largest vascular organs in the body, clinical and surgical cases have given an incidence of 3% of secondary malignances of the organ. Nevertheless, thyroid metastases are not an exceptional finding at autopsy, they are encountered in 2% to 24% of the patients with malignant neoplasm.Soft tissue sarcomas metastatic to the thyroid are extremely rare as the majority of thyroid metastasis are caused by tumors of the kidneys, lungs, mammary glands, ovaries , and colon or by melanomas.We report a case of 22-years-old woman with right leg rhabdomyosarcoma metastatic to the thyroid gland.

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Figures

Figure 1
Figure 1
Total Thyroidectomy, the right lobe shown to be large with infiltration of Rt common carotid artery.
Figure 2
Figure 2
The sarcoma tissue invades between the thyroid follicles (H&E x100) (A). The tumour cells show significant pleomorphism (H&E x200), (B), diffuse immunoreactivity to vimentin (DAB peroxidase x100) (C) and desmin (DAB peroxidase x200) (D).
See this image and copyright information in PMC

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