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Review
. 2012 Aug;18(4):277-90.
doi: 10.1007/s13365-012-0108-z. Epub 2012 May 30.

Neuropsychiatric complications of aging with HIV

Affiliations
Review

Neuropsychiatric complications of aging with HIV

Crystal C Watkins et al. J Neurovirol. 2012 Aug.

Abstract

Persons over age 50 are not only aging with human immunodeficiency virus (HIV) infection but also represent a high proportion of new HIV infections. Neuropsychiatric symptoms, including depression, cognitive impairment, and substance abuse, are very common in individuals infected with HIV. However, there is little understanding of the relationship between these HIV-related comorbid conditions in newly infected elderly patients compared to uninfected elderly and those who have survived after 20 years of HIV/AIDS. We summarize the current theories and research that link aging and HIV with psychiatric illnesses and identify emerging areas for improved research, treatment, and patient care.

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Figures

Fig. 1
Fig. 1
Aging with HIV and its effects on related neuropsychiatric illnesses

References

    1. Alciati A, Starace F, Scaramelli B, Campaniello M, Adriani B, Mellado C, Cargnel A. Has there been a decrease in the prevalence of mood disorders in HIV-seropositive individuals since the introduction of combination therapy? Eur Psychiatry. 2001;16:491–496. - PubMed
    1. Alciati A, Gallo L, Monforte AD, Brambilla F, Mellado C. Major depression-related immunological changes and combination antiretroviral therapy in HIV-seropositive patients. Hum Psychopharmacol. 2007;22:33–40. - PubMed
    1. Angelino AF, Treisman GJ. Issues in co-morbid severe mental illnesses in HIV infected individuals. Int Rev Psychiatry. 2008;20:95–101. - PubMed
    1. Azar MM, Springer SA, Meyer JP, Altice FL. A systematic review of the impact of alcohol use disorders on HIV treatment outcomes, adherence to antiretroviral therapy and health care utilization. Drug Alcohol Depend. 2010;112:178–93. - PMC - PubMed
    1. Becker JT, Lopez OL, Dew MA, Aizenstein HJ. Prevalence of cognitive disorders differs as a function of age in HIV virus infection. AIDS. 2004;18(Suppl 1):S11–S18. - PubMed

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