Cardiovascular risk in patients with psoriatic arthritis
- PMID: 22645614
- PMCID: PMC3356896
- DOI: 10.1155/2012/714321
Cardiovascular risk in patients with psoriatic arthritis
Abstract
Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. In addition to skin and joint involvement, there is increasing evidence suggesting that patients with PsA also have an increase in risk of clinical and subclinical cardiovascular diseases, mostly due to accelerating atherosclerosis. Both conventional and nonconventional cardiovascular risk factors contribute to the increased cardiovascular risk in PsA. Chronic inflammation plays a pivotal role in the pathogenesis of atherosclerosis in PsA, acting independently and/or synergistically with the conventional risk factors. In this paper, we discuss the current literature indicating that patients with PsA are at risk of cardiovascular diseases.
References
-
- Alamanos Y, Voulgari PV, Drosos AA. Incidence and prevalence of psoriatic arthritis: a systematic review. Journal of Rheumatology. 2008;35(7):1354–1358. - PubMed
-
- Gladman DD, Shuckett R, Russell ML. Psoriatic arthritis (PSA)—an analysis of 220 patients. Quarterly Journal of Medicine. 1987;62(238):127–141. - PubMed
-
- McHugh NJ, Balachrishnan C, Jones SM. Progression of peripheral joint disease in psoriatic arthritis: a 5-yr prospective study. Rheumatology. 2003;42(6):778–783. - PubMed
-
- Kane D, Stafford L, Bresniham B, FitzGerard O. A prospective, clinical and radiological study of early psoriatic arthritis: an early synovitis clinic experience. Rheumatology. 2003;42(12):1460–1468. - PubMed
-
- Peters MJ, Van Der Horst-Bruinsma IE, Dijkmans BA, Nurmohamed MT. Cardiovascular risk profile of patients with spondylarthropathies, particularly ankylosing spondylitis and psoriatic arthritis. Seminars in Arthritis and Rheumatism. 2004;34(3):585–592. - PubMed
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