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. 2012 May 30:5:103.
doi: 10.1186/1756-3305-5-103.

Seasonal performance of a malaria rapid diagnosis test at community health clinics in a malaria-hyperendemic region of Burkina Faso

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Seasonal performance of a malaria rapid diagnosis test at community health clinics in a malaria-hyperendemic region of Burkina Faso

Amidou Diarra et al. Parasit Vectors. .

Abstract

Background: Treatment of confirmed malaria patients with Artemisinin-based Combination Therapy (ACT) at remote areas is the goal of many anti-malaria programs. Introduction of effective and affordable malaria Rapid Diagnosis Test (RDT) in remote areas could be an alternative tool for malaria case management. This study aimed to assess performance of the OptiMAL dipstick for rapid malaria diagnosis in children under five.

Methods: Malaria symptomatic and asymptomatic children were recruited in a passive manner in two community clinics (CCs). Malaria diagnosis by microscopy and RDT were performed. Performance of the tests was determined.

Results: RDT showed similar ability (61.2%) to accurately diagnose malaria as microscopy (61.1%). OptiMAL showed a high level of sensitivity and specificity, compared with microscopy, during both transmission seasons (high & low), with a sensitivity of 92.9% vs. 74.9% and a specificity of 77.2% vs. 87.5%.

Conclusion: By improving the performance of the test through accurate and continuous quality control of the device in the field, OptiMAL could be suitable for use at CCs for the management and control of malaria.

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References

    1. Dicko A, Mantel C, Kouriba B, Sagara I, Thera MA, Doumbia S, Diallo M, Poudiougou B, Diakite M, Doumbo OK. Season, fever prevalence and pyrogenic threshold for malaria disease definition in an endemic area of Mali. Trop Med Int Health. 2005;10(6):550–556. doi: 10.1111/j.1365-3156.2005.01418.x. - DOI - PubMed
    1. Reyburn H, Ruanda J, Mwerinde O, Drakeley C. The contribution of microscopy to targeting antimalarial treatment in a low transmission area of Tanzania. Malar J. 2006;5:4. doi: 10.1186/1475-2875-5-4. - DOI - PMC - PubMed
    1. Wongsrichanalai C, Barcus MJ, Muth S, Sutamihardja A, Wernsdorfer WH. A review of malaria diagnostic tools: microscopy and rapid diagnostic test (RDT) Am J Trop Med Hyg. 2007;77(6 Suppl):119–127. - PubMed
    1. Sirima BSI, Tiono AB, Konate AT. Données de base pour le suivi et l'évaluation de l'initiative "Faire reculer le Paludisme" et "Situation de la mise en oeuvre de l'initiative "Faire Reculer le Paludisme"dans les zones pilotes. Ouagadougou, Programme National de Lutte contre le Paludisme. 2003. pp. 54–72.
    1. Pfeiffer K, Some F, Muller O, Sie A, Kouyate B, Haefeli WE, Zoungrana A, Gustafsson LL, Tomson G, Sauerborn R. Clinical diagnosis of malaria and the risk of chloroquine self-medication in rural health centres in Burkina Faso. Trop Med Int Health. 2008;13(3):418–426. doi: 10.1111/j.1365-3156.2008.02017.x. - DOI - PubMed

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