Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Jul 3;24(25):3309-14.
doi: 10.1002/adma.201200785. Epub 2012 May 31.

Near-infrared light-responsive intracellular drug and siRNA release using au nanoensembles with oligonucleotide-capped silica shell

Yi-Ting Chang  1 , Pei-Yi Liao, Hwo-Shuenn Sheu, Yu-Jui Tseng, Fong-Yu Cheng, Chen-Sheng Yeh
Affiliations

Near-infrared light-responsive intracellular drug and siRNA release using au nanoensembles with oligonucleotide-capped silica shell

Yi-Ting Chang et al. Adv Mater. .

Abstract

Taking advantage of the character of Au nanorods (NRs) to absorb NIR light, a NIR-responsive oligonucleotide-gated ensemble is developed to perform intracellular drug delivery. Using an oligonucleotide bio-gate enables siRNA release into cells for translational regulation as well as cytotoxicity in anti-cancer drug delivery.

PubMed Disclaimer

Publication types

LinkOut - more resources