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. 2012 Jun 15;14(12):3044-7.
doi: 10.1021/ol3011198. Epub 2012 May 31.

Ketone formation via mild nickel-catalyzed reductive coupling of alkyl halides with aryl acid chlorides

Fan Wu  1 , Wenbin Lu, Qun Qian, Qinghua Ren, Hegui Gong
Affiliations

Ketone formation via mild nickel-catalyzed reductive coupling of alkyl halides with aryl acid chlorides

Fan Wu et al. Org Lett. .

Abstract

The present work highlights unprecedented Ni-catalyzed reductive coupling of unactivated alkyl iodides with aryl acid chlorides to efficiently generate alkyl aryl ketones under mild conditions.

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