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Editorial
. 2012 Jun;20(6):1077-8.
doi: 10.1038/mt.2012.91.

The challenge of using gene- or cell-based therapies to treat lung disease

Ronald G Crystal
Editorial

The challenge of using gene- or cell-based therapies to treat lung disease

Ronald G Crystal. Mol Ther. 2012 Jun.
No abstract available

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Figures

Figure 1
Figure 1
Combining gene transfer and stem/progenitor cell therapy to safely regenerate functional lung. Although stem/progenitor cell technology holds great promise for lung regeneration, there is the risk that the cells, once transplanted, will go awry, resulting in disordered lung and, at worst, malignant transformation. One solution is to genetically modify the stem/progenitor cells with suicide genes that could be switched on, deleting the transplanted cells and their progeny.
See this image and copyright information in PMC

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References

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