Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Jun;73(3):190-3.
doi: 10.1007/s12262-010-0193-2. Epub 2011 Jan 27.

Role of prophylactic antibiotics in open inguinal hernia repair: a randomised study

Affiliations

Role of prophylactic antibiotics in open inguinal hernia repair: a randomised study

Amit Goyal et al. Indian J Surg. 2011 Jun.

Abstract

To study the role of prophylactic antibiotics in open inguinal hernia repair. A total of 200 patients were included, they were randomised in two groups. Group 1 was given prophylactic dose of inj amoxy-clav while group 2 was given placebo only. Results were compared and Data analysed using the Chi-square test. Complications in both the groups were compared. Rate of serous discharge and seroma formation was 1% and 22% respectively in group 1 while 2% and 26% in group 2 also the rate of erythema and stitch abscess were 1% and none in group 1 and 2% and 1% in group 2 respectively. On statistical analysis these differences were not significant. Addition of prophylactic antibiotics in elective open inguinal hernia repair has no significant benefit over placebo although larger studies are required to prepare some uniform guidelines.

Keywords: Hernia; Mesh repair; Prophylactic antibiotics.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Bar diagram comparing complications in both groups

References

    1. Burke JF. The effective period of preventive antibiotic action in experimental incision and dermal lesions. Surgery. 1961;50:161–168. - PubMed
    1. Haley RW, Culver DH, Morgan WM, et al. Identifying Patients at high risk of surgical wound in infections. A simple multivariate index of patient susceptibility and wound contamination. Am J of Epidemiology. 1985;121:206–215. - PubMed
    1. Cainzos MA. Antibiotic prophylaxis. New Horiz. 1998;6(2):S11–S17. - PubMed
    1. Condon RE, Wittmann DH. The use of antibiotics in general surgery. Curr Probl Surg. 1991;28:803–907. doi: 10.1016/0011-3840(91)90004-9. - DOI - PubMed
    1. Woods RK, Dellinger EP. Current guidelines for antibiotic prophylaxis of surgical wounds. Am Family Physician. 1998;57:2731–2734. - PubMed

LinkOut - more resources