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Review
. 2012:2012:151967.
doi: 10.1155/2012/151967. Epub 2012 May 10.

Commercial dengue rapid diagnostic tests for point-of-care application: recent evaluations and future needs?

Stuart D Blacksell  1
Affiliations
Review

Commercial dengue rapid diagnostic tests for point-of-care application: recent evaluations and future needs?

Stuart D Blacksell. J Biomed Biotechnol. 2012.

Abstract

Dengue fever, dengue haemorrhagic fever, and dengue shock syndrome (DF/DHF/DSS) are tropical diseases that cause significant humanitarian and economic hardship. It is estimated that more than 2.5 billion people are at risk of infection and more than 100 countries have endemic dengue virus transmission. Laboratory tests are essential to provide an accurate diagnosis of dengue virus infection so that appropriate treatment and patient management may be administered. In many dengue endemic settings, laboratory diagnostic resources are limited and simple rapid diagnostic tests (RDTs) provide opportunities for point-of-care diagnosis. This paper addresses current issues relating to the application of commercial dengue RDTs for the diagnosis of acute dengue virus infection, recent diagnostic evaluations, and identifies future needs.

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Figures

Figure 1
Figure 1
Graphical representation of the kinetics of dengue NS1 antigen and IgM, IgG, and IgA antibodies during a primary dengue infection.
Figure 2
Figure 2
Graphical representation of the kinetics of dengue NS1 antigen and IgM, IgG, and IgA antibodies during a secondary dengue infection.
See this image and copyright information in PMC

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