Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1990 Oct;228(4):409-10.
doi: 10.1111/j.1365-2796.1990.tb00254.x.

Gall-bladder perforation after long-term dapsone therapy

A M Choy  1 , C C Lang
Affiliations
Case Reports

Gall-bladder perforation after long-term dapsone therapy

A M Choy et al. J Intern Med. 1990 Oct.

Abstract

A 65-year-old man on maintenance dapsone therapy for dermatitis herpetiformis for 30 years was admitted to hospital with acute abdominal pain and vomiting. Investigations revealed a Heinz body haemolytic anaemia. Worsening symptoms prompted an emergency laparotomy that revealed a perforated gall bladder with pigmented biliary calculi. In previous reviews of the haematological abnormalities associated with dapsone therapy, life-threatening cholecystitis has not been described.

PubMed Disclaimer

Publication types

LinkOut - more resources