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Editorial
. 2012 May-Jun;64(3):270-2.
doi: 10.1016/S0019-4832(12)60085-6.

Composite risk scores for acute coronary syndromes

Editorial

Composite risk scores for acute coronary syndromes

K Sarat Chandra. Indian Heart J. 2012 May-Jun.

Abstract

There have been considerable advances in the management of acute coronary syndromes in the recent past. There are three risk scoring systems used for prognosticating these patients. An attempt is made in this article to discuss the pros and cons of the different risk scoring systems and their clinical utility.

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Figures

Figure 1
Figure 1
Use of the TIMI risk score for UA/NSTEMI to predict the benefit of an early invasive strategy. In a prospectively defined analysis, the TIMI risk score was applied in the Treat Angina with Aggrastat and determine Cost of Therapy with an Invasive or Conservative Strategy (TACTICS-TIMI 18 trial. As shown, 75% of patients had a risk score of three or higher, and a significant benefit of an invasive strategy was observed in these patients). (Data from Cannan CP, Weintraub WS, Demopoulos LA, et al. Comparison of early invasive and conservative strategy in unstable coronary syndromes treated with Glycoprotein IIb/IIIa inhibitor Tirofiban. NEJM 2001;344:1879–87). CI: confidence interval, CONS: conservative, INV: invasive, MI: myocardial infarction, OR: odds ratio, TIMI: thrombolysis in myocardial infarction.
Figure 2
Figure 2
Thrombolysis in myocardial ischaemia risk score for unstable angina or non-ST-elevation myocardial infarction (UA/NSTEMI). The risk factors are shown at the bottom, and the risk of death (D), myocardial infarction, or urgent revascularisation is shown along the vertical axis. (Modified from Antman EM, Cohen M, Bernink PJLM, et al. The TIMI risk score for unstable angina/non-ST elevation MI: a method for prognostication and therapeutic decision-making. JAMA 2000;284:835). CAD: coronary artery disease, ECG: electrocardiogram, TIMI: thrombolysis in myocardial infarction.

Comment on

References

    1. Neumann FJ, Kastrati A, Pogasta-Murray V. Evaluation of proglonged anti-thrombotic pre treatment (Coling-of-strategy) before intervention in patients with unstable coronary syndromes: a randomized control trial. JAMA. 2003;290:1593–1599. - PubMed
    1. Mehta SR, Granger CB, Doden WE. Early versus delayed invasive intervention in acute coronary syndromes. NEJM. 2009;360:2165–2175. - PubMed
    1. Antman EM. TIMI 11B. Enoxaparin versus unfractionated heparin for unstable angina or non-Q-wave myocardial infarction: a double-blind, placebo-controlled, parallel-group, multicenter trial. Rationale, study design, and methods. Thrombolysis in Myocardial Infarction (TIMI) 11B Trial Investigators. Am Heart J. 1998;135(6 Pt 3 Su):S353–S360. - PubMed
    1. Cannan CP, Weintraub WS, Demopoulos LA. Comparison of early invasive and conservative strategy in unstable coronary syndromes treated with glycoprotein IIb/IIIa inhibitor Tirofiban. NEJM. 2001;344:1879–1887. - PubMed
    1. Granger CB, GoldBerg RJ, Dabbous O. Predictors of Hospital mortality in the global registry of acute coronary events. Arch Intern Med. 2003;163:2345–2353. - PubMed