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. 2009 Dec;1(7):377-80.
doi: 10.4297/najms.2009.7377.

Familial early onset of type-2 diabetes mellitus and its complications

Mallikarjun V Jali  1 , Sanjay Kambar, Sujata M Jali, Shivaraj Gowda
Affiliations

Familial early onset of type-2 diabetes mellitus and its complications

Mallikarjun V Jali et al. N Am J Med Sci. 2009 Dec.

Abstract

Background: Globally, the prevalence of chronic, non-communicable diseases is increasing at an alarming rate. Furthermore, approximately 197 million people worldwide have impaired glucose tolerance. Consequently, diabetes is rapidly emerging as a global health problem that threatens to assume a pandemic level by 2030. In Indian population, genetic predisposition to trigger diabetes at an early age as compared to western counterpart has been focused very much.

Aim: To gain further insight into the positive correlation between the diabetes and family history was the objective of this study.

Materials and methods: Patients attending the Diabetes Centre, K.L.E.S Dr. Prabhakar. Kore Hospital and Medical Research Centre; J. N. Medical College; KLE University Belgaum, Karnataka- India, were recruited, diagnosed and analyzed as per WHO criteria.

Results: The prevalence of diabetes was higher among patients with diabetic mother (25.6%) compared to patients with diabetic father (21.2%) and there was early onset of type -2 diabetes among patients having both parents with diabetic when compared to other patients.

Conclusion: Based on the present observation, it would be appropriate to emphasize again that a strong family history for diabetes, would signal at an early age, the onset of diabetes perhaps with its complications.

Keywords: Family history; nephropathy.; retinopathy; type-2 diabetes mellitus.

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