Atopic dermatitis: a candidate for disease-modifying strategy
- PMID: 22671706
- DOI: 10.1111/j.1398-9995.2012.02845.x
Atopic dermatitis: a candidate for disease-modifying strategy
Abstract
The concept of disease modification has been introduced to define the therapeutic strategies aimed to break, stop, or reverse the natural course of a chronic invalidating disease. This strategy is tightly related to the biomarker-based stratification of affected patients using genetic and other biological markers. With regard to the progress in understanding the genetic background of atopic dermatitis (AD), its natural history and its pivotal role in the emergence of allergic asthma, the time is mature to foster the research field of biomarkers in AD and to consider the elaboration of disease-modifying strategies in the management of AD with the goal to stop or even reverse the atopic march.
© 2012 John Wiley & Sons A/S.
Comment in
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The switch from non-IgE-associated to IgE-associated atopic dermatitis occurs early in life.Allergy. 2013 Feb;68(2):259-60. doi: 10.1111/all.12070. Allergy. 2013. PMID: 23320563 No abstract available.
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