Cancers co-opt cohabitants' catabolism: autophagy and senescence in the tumor stroma
- PMID: 22672908
- PMCID: PMC3383584
- DOI: 10.4161/cc.20964
Cancers co-opt cohabitants' catabolism: autophagy and senescence in the tumor stroma
Abstract
Comment on: Capparelli C, et al. Cell Cycle 2012; 11:2272-84 and Capparelli C, et al. Cell Cycle 2012; 11:2285-302.
Comment on
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Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production.Cell Cycle. 2012 Jun 15;11(12):2285-302. doi: 10.4161/cc.20718. Epub 2012 Jun 15. Cell Cycle. 2012. PMID: 22684298 Free PMC article.
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CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth.Cell Cycle. 2012 Jun 15;11(12):2272-84. doi: 10.4161/cc.20717. Epub 2012 Jun 15. Cell Cycle. 2012. PMID: 22684333 Free PMC article.
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