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. 2012 Nov;16(8):2319-29.
doi: 10.1007/s10461-012-0222-1.

Do coping styles mediate the relationship between substance use and educational attainment and antiretroviral adherence?

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Do coping styles mediate the relationship between substance use and educational attainment and antiretroviral adherence?

David A Martinez et al. AIDS Behav. 2012 Nov.

Abstract

There is a substantial body of literature that demonstrates that substance use and lower educational attainment are associated with poorer antiretroviral (ART) adherence, however, the nature of these relationships are not well understood. The purpose of this study was to explore whether coping styles mediate the relationship between substance use and educational attainment and ART adherence in order to better understand how these variables relate to adherence. The sample consisted of 192 HIV-positive patients (mean age = 41 years; 75.5 % male, 46.9 % heterosexual; 52.6 % with a high school/GED education or less) who were on ART. Path analysis revealed that active and avoidant coping significantly mediated the relationship between drug use and ART adherence. No form of coping was found to mediate the relationship between either binge drinking or educational attainment and adherence. Findings suggest that a focus on coping skills should be included in any multimodal intervention to increase ART adherence among HIV-positive drug using patients.

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Figures

Fig. 1
Fig. 1
Initial path model: coping styles (active coping, avoidant coping, CRC, SDRC, and PRDC) as mediators of the relationship between substance use and educational attainment and ART adherence. χ2 = 153.173, df = 10, p < .05; CMIN/DF = 15.317; RMSEA = .275 (.236, .313), p < .001; CFI = .233. This model accounted for 9 % of variance
Fig. 2
Fig. 2
Final path model: coping styles as mediators of the relationship between substance use and educational attainment and ART adherence. Fit indices indicate good model fit: χ2 = 15.629, df = 9, p > .05; CMIN/DF = 1.737; RMSEA = .062 (.000, .112), p > .05; CFI = .855. ** p < .005; * p < .05. PRDC = passive religious deferral coping

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References

    1. Gulick RM, Mellors JW, Havlir D, et al. Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy. N Engl J Med. 1997;337:734–9. - PubMed
    1. McMahon D, Lederman M, Haas DW, et al. Antiretroviral activity and safety of abacavir in combination with selected HIV-1 protease inhibitors in therapy-naïve HIV-1 infected adults. Antivir Ther. 2001;6(2):105–14. - PubMed
    1. Saag MS, Tebas P, Sension M, et al. Randomized, double-blind comparison of two nelfinavir doses plus nucleosides in HIV-infected patients (Agouron study 511) AIDS. 2001;15(15):1971–8. - PubMed
    1. Staszewski S, Morales-Ramirez J, Tashima KT, et al. Efavirenz plus zidovudine and lamivudine in the treatment of HIV-1 infection in adults. New Engl J Med. 1999;341(25):1865–73. - PubMed
    1. Cameron DW, Heath-Chiozzi M, Danner S, et al. Randomised placebo-controlled trial of ritonavir in advanced HIV-1 disease. Lancet. 1998;351(9102):543–9. - PubMed

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