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Review
. 2012 Jul 10:11:67.
doi: 10.1186/1476-511X-11-67.

Dietary whey protein lessens several risk factors for metabolic diseases: a review

Gabriela T D Sousa  1 , Fábio S Lira, José C Rosa, Erick P de Oliveira, Lila M Oyama, Ronaldo V Santos, Gustavo D Pimentel
Affiliations
Review

Dietary whey protein lessens several risk factors for metabolic diseases: a review

Gabriela T D Sousa et al. Lipids Health Dis. .

Abstract

Obesity and type 2 diabetes mellitus (DM) have grown in prevalence around the world, and recently, related diseases have been considered epidemic. Given the high cost of treatment of obesity/DM-associated diseases, strategies such as dietary manipulation have been widely studied; among them, the whey protein diet has reached popularity because it has been suggested as a strategy for the prevention and treatment of obesity and DM in both humans and animals. Among its main actions, the following activities stand out: reduction of serum glucose in healthy individuals, impaired glucose tolerance in DM and obese patients; reduction in body weight; maintenance of muscle mass; increases in the release of anorectic hormones such as cholecystokinin, leptin, and glucagon like-peptide 1 (GLP-1); and a decrease in the orexigenic hormone ghrelin. Furthermore, studies have shown that whey protein can also lead to reductions in blood pressure, inflammation, and oxidative stress.

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Figures

Figure 1
Figure 1
Main mechanisms of action of whey protein in protection of risk factors for metabolic diseases, such as obesity, type 2 diabetes mellitus, hypertension, oxidative stress and metabolic syndrome.
See this image and copyright information in PMC

References

    1. Giskes K, van Lenthe F, Avendano-Pabon M, Brug J. A systematic review of environmental factors and obesogenic dietary intakes among adults: are we getting closer to understanding obesogenic environments? Obes Rev. 2011;12:e95–e106. doi: 10.1111/j.1467-789X.2010.00769.x. - DOI - PubMed
    1. Pimentel GD, Arimura ST, de Moura BM, Silva ME, de Sousa MV. Short-term nutritional counseling reduces body mass index, waist circumference, triceps skinfold and triglycerides in women with metabolic syndrome. Diabetol Metab Syndr. 2010;2:13. doi: 10.1186/1758-5996-2-13. - DOI - PMC - PubMed
    1. WHO. Global strategy on diet, physical activity and health: obesity and overweight. World Health Organization, Geneva; 2012. http://www.who.int/dietphysicalactivity/publications/facts/obesity/en/
    1. Misra A, Khurana L. Obesity-related non-communicable diseases: South Asians vs White Caucasians. Int J Obes (Lond) 2011;35:167–187. doi: 10.1038/ijo.2010.135. - DOI - PubMed
    1. Gigante DP, Moura EC, Sardinha LM. Prevalence of overweight and obesity and associated factors, Brazil, 2006. Rev Saude Publica. 2009;43(Suppl 2):83–89. - PubMed

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