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Case Reports
. 2011 Aug 19:2011:bcr0620114419.
doi: 10.1136/bcr.06.2011.4419.

'Goose bumps'-associated anaemia

Chisho Hoshino  1 , Akane Yamabe, Yoshiyuki Sekikawa, Kana Ishihara, Hiroshi Ikeda, Noriyuki Satoh, Masashi Narita, Minoru Inoue
Affiliations
Case Reports

'Goose bumps'-associated anaemia

Chisho Hoshino et al. BMJ Case Rep. .

Abstract

A 36-year-old woman presented to our hospital for further evaluation of anaemia screened by regular check-up. She was diagnosed with iron-deficiency anaemia (IDA) but refractory to iron supplementation. She had negative results of occult blood in the stool and no gynaecologic disease potentially causing hyper menorrhea. Upper endoscopy revealed a nodular gastritis, which has been called 'Torihada-ien', a Japanese word meaning 'gastritis with goose bumps-like appearance', associated with Helicobacter pylori (Hp) infection. After Hp eradication therapy, her anaemia resolved with an improved response to iron supplementation. In an unexplained IDA patient, Hp-associated gastritis should be considered in the possible background.

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Conflict of interest statement

Competing interests None.

Figures

Figure 1
Figure 1
Upper endoscopy revealed diffuse gastric nodularity 2 to 3 mm in diameter from the antrum to angulus without any mucosal erosion, ulcer or atrophy.
Figure 2
Figure 2
On histological examination, a biopsy specimen from the antrum showed marked inflammatory cell infiltration with lymphoid follicles (Haematoxylin-Eosin stain, ×10).
See this image and copyright information in PMC

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