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Case Reports
. 2011 Sep 28:2011:bcr0820114605.
doi: 10.1136/bcr.08.2011.4605.

Touraine-Solente-Gole' syndrome

Affiliations
Case Reports

Touraine-Solente-Gole' syndrome

Monica Gupta et al. BMJ Case Rep. .

Abstract

Touraine-Solente-Gole' syndrome, also known as pachydermoperiostosis or primary hypertrophic osteoarthropathy is a rare familial disorder generally seen in males. Although it presents with characteristic morphological and radiological features, this is an uncommon diagnosis and is entertained only once other causes of secondary hypertrophic osteoarthropathy are carefully excluded.

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Conflict of interest statement

Competing interests None.

Figures

Figure 1
Figure 1
Clinical photograph showing deep furrows on forehead.
Figure 2
Figure 2
Clinical photograph showing coarsening of palmar creases.
Figure 3
Figure 3
Clinical photograph showing large spade-like hands with broadened wrists.
Figure 4
Figure 4
Clinical photograph showing enlargement of the distal part of the lower extremities.
Figure 5
Figure 5
Clinical photograph showing ankle joint arthritis.
Figure 6
Figure 6
Radiograph of the leg (tibia and fibula) depicting irregular bony surfaces.
Figure 7
Figure 7
Radiograph of the foot depicting subperiosteal new bone formation.
Figure 8
Figure 8
Radiograph of the forearm (radius and ulna) depicting irregular outline.

References

    1. Eckardt A, Kreitner KF. [Primary hypertrophic osteoarthropathy]. Z Orthop Ihre Grenzgeb 1995;133:303–5 - PubMed
    1. Friedreich N. Hyperostose des gesammten skelettes. Virchows Arch Pathol Anat 1868;43:83
    1. Touraine A, Solente G, Gole L. Un syndrome osteodermopathique: la pachydermie plicaturee avec pachyperiostose ds extremites. Presse Med 1935;43:1820–4
    1. Gilliland BC. Fibromyalgia, arthritis associated with systemic disease, and other arthritis. Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL, Jameson LL, eds. Harrison’s Principles of Internal Medicine. New York, NY: Mc-Graw Hill companies; 2005:2055–64
    1. Sayli U, Yetkin H, Atik OS, et al. Pachydermoperiostosis: a case report. J Foot Ankle Surg 1993;32:480–3 - PubMed

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