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Review
. 1990:592:25-37.

Human neuroblastoma cells in culture: a model for neuronal cell differentiation and function

Affiliations
  • PMID: 2267941
Review

Human neuroblastoma cells in culture: a model for neuronal cell differentiation and function

S Påhlman et al. Acta Physiol Scand Suppl. 1990.

Abstract

The human neuroblastoma cell line, SH-SY5Y, differentiates into neuron-like cells according to morphological, biochemical and functional criteria when treated with biologically active phorbol-esters. The differentiated phenotype is described and alterations in proto-oncogene expression in connection with growth control and differentiation are presented and discussed.

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