Human neuroblastoma cells in culture: a model for neuronal cell differentiation and function
- PMID: 2267941
Human neuroblastoma cells in culture: a model for neuronal cell differentiation and function
Abstract
The human neuroblastoma cell line, SH-SY5Y, differentiates into neuron-like cells according to morphological, biochemical and functional criteria when treated with biologically active phorbol-esters. The differentiated phenotype is described and alterations in proto-oncogene expression in connection with growth control and differentiation are presented and discussed.
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