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Review
. 2012 Dec;11(6):422-32.
doi: 10.2174/187152812803590028.

Pentoxifylline use in dermatology

Seray Külcü Çakmak  1 , Atil Çakmak, Müzeyyen Gönül, Arzu Kiliç, Ülker Gül
Affiliations
Review

Pentoxifylline use in dermatology

Seray Külcü Çakmak et al. Inflamm Allergy Drug Targets. 2012 Dec.

Abstract

Pentoxifylline is methylxanthine derivative which is used in microcirculatory disorders as a vasoactive drug. Novel immunomodulatory properties of pentoxifylline have been reported including the down regulation of tumour necrosis factor-α synthesis and other inflammatory cytokines. Studies have shown that pentoxifylline might be efficacious in a wide spectrum of skin diseases. This article focuses on the use of pentoxifylline which is a safe and cheap drug in various dermatological disorders.

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