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. 2012 Jun;18(2):213-20.
doi: 10.1177/159101991201800215. Epub 2012 Jun 4.

Symptomatic middle cerebral artery stenosis treated by percutaneous transluminal angioplasty: improvement of cerebrovascular reserves

A Abe  1 , T Ueda, M Ueda, S Nogoshi, Y Nishiyama, Y Katayama
Affiliations

Symptomatic middle cerebral artery stenosis treated by percutaneous transluminal angioplasty: improvement of cerebrovascular reserves

A Abe et al. Interv Neuroradiol. 2012 Jun.

Abstract

This study evaluated the recoveries of cerebrovascular reserves (CVR) after applying percutaneous transluminal angioplasty (PTA) to patients with symptomatic middle cerebral artery (MCA) stenosis of varying severity. The patients were submitted to single photon emission computed tomography (SPECT) to obtain their regional cerebral blood flows at resting stage (rCBF(rest)) and acetazolamide-challenged CBF in five regions of interest (ROIs), including the MCA, on the ipsilateral and contralateral sides of the hemisphere. rCVR values were then calculated from these CBF data to evaluate the CVR recoveries after PTA treatment. When the PTA effects were statistically analyzed of the patients dichotomized into more severe (n=9) and less severe (n=5) groups, distinctly significant ROI-specific PTA effectiveness was observed for CVR rather than CBF values in the patients of the severer group.

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Figures

Figure 1
Figure 1
Regional cerebrovascular reserves (rCVRs) in 5 regions of interest (ROIs) on hemispheric ipsilateral and contralateral sides of sever and less-severe subject groups before and after percutaneous transluminal angioplasty (PTA) treatment. Each column represent a mean + standard deviation.
See this image and copyright information in PMC

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