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Comment
. 2012 Jun 6;15(6):795-7.
doi: 10.1016/j.cmet.2012.05.007.

Hidden variant of ChREBP in fat links lipogenesis to insulin sensitivity

Renaud Dentin  1 , Dominique Langin, Catherine Postic
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Free article
Comment

Hidden variant of ChREBP in fat links lipogenesis to insulin sensitivity

Renaud Dentin et al. Cell Metab. .
Free article

Abstract

The ChREBP transcription factor is regulated by glucose and plays a role in insulin sensitivity, but the mechanism underlying these effects remains unclear. In a recent Nature article, Herman et al. (2012) show that a shorter ChREBP isoform (ChREBP-β) links glucose transport to lipogenesis in white adipose tissue.

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