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Review
. 2012 Jun 8;149(6):1188-91.
doi: 10.1016/j.cell.2012.05.022.

Getting RNA and protein in phase

Stephanie C Weber  1 , Clifford P Brangwynne
Affiliations
Free article
Review

Getting RNA and protein in phase

Stephanie C Weber et al. Cell. .
Free article

Abstract

Nonmembrane-bound organelles such as RNA granules behave like dynamic droplets, but the molecular details of their assembly are poorly understood. Several recent papers identify structural features that drive granule assembly, shedding light on how phase transitions functionally organize the cell and may lead to pathological protein aggregation.

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