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Review
. 2012 Dec;55(6):641-7.
doi: 10.1097/MPG.0b013e3182617a9d.

Immune factors in breast milk and the development of atopic disease

Shuba R Iyengar  1 , W A Walker
Affiliations
Review

Immune factors in breast milk and the development of atopic disease

Shuba R Iyengar et al. J Pediatr Gastroenterol Nutr. 2012 Dec.

Abstract

Breast-feeding provides protection against infections and contains numerous factors that modulate and promote the development of the infant immune system. These factors include secretory IgA, antimicrobial proteins like CD14, cytokines, and fatty acids. Studies examining the role of breast-feeding in the development of allergic disease in infants demonstrate potentially protective as well as neutral or nonprotective effects, likely due to the heterogeneity in their study design. In this overview, we explore the potential role of immune factors in the breast milk, as well as selected probiotics, in the development of allergy.

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Comment in

  • Stop considering atopic dermatitis as an allergic disease.
    Bramuzzo M, Longo G, Ventura A. Bramuzzo M, et al. J Pediatr Gastroenterol Nutr. 2013 Jul;57(1):e9. doi: 10.1097/MPG.0b013e3182923772. J Pediatr Gastroenterol Nutr. 2013. PMID: 23535764 No abstract available.
  • Authors' response.
    Walker WA, Iyengar R. Walker WA, et al. J Pediatr Gastroenterol Nutr. 2013 Jul;57(1):e9-10. doi: 10.1097/mpg.0b013e3182923787. J Pediatr Gastroenterol Nutr. 2013. PMID: 23961548 No abstract available.

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