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. 2012 Jan-Mar;27(1):49-54.

Progression to dementia in a population with amnestic mild cognitive impairment: clinical variables associated with conversion

Marco Mauri  1 , Elena Sinforiani, Chiara Zucchella, Maria Giovanna Cuzzoni, Giorgio Bono
Affiliations

Progression to dementia in a population with amnestic mild cognitive impairment: clinical variables associated with conversion

Marco Mauri et al. Funct Neurol. 2012 Jan-Mar.

Abstract

The aim of this study was to investigate clinical predictors of, and rates of conversion to, dementia syndrome in a case series of patients with amnestic mild cognitive impairment (aMCI). Two hundred and eight aMCI subjects were followed over a six-year period. A lower Mini Mental State Examination score was a significant predictor of dementia, and mild cognitive impairment patients with behavioral and psychiatric symptoms showed a faster conversion rate.

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Figures

Figure 1
Figure 1
Amnestic mild cognitive impairment: annual rate of conversion to dementia (143/208 cases)
Figure 2
Figure 2
Effect of MMSE score on conversion to dementia (0:score 28–30, 1:score 25–27)
Figure 3
Figure 3
Overall percentages of different neuropsychiatric symptoms (NPI score ≥4) in amnesic MCI patients
See this image and copyright information in PMC

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