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Case Reports
. 2011 Aug 4:2011:bcr0520114220.
doi: 10.1136/bcr.05.2011.4220.

Hepatic nodule: a case of primary myelofibrosis

Filipe Sousa Cardoso  1 , João Veríssimo Pires, José Simão Miranda, João Mascarenhas Araújo
Affiliations
Case Reports

Hepatic nodule: a case of primary myelofibrosis

Filipe Sousa Cardoso et al. BMJ Case Rep. .

Abstract

Primary myelofibrosis is one of the entities that may manifest with lesions of extramedullary haematopoiesis, especially in spleen and liver. The authors report a case of primary myelofibrosis presenting incidentally as an intrahepatic focal lesion of extramedullary haematopoiesis, a rare occurrence that highlights the challenge of hepatic nodule differential diagnosis, and allows reflection about the diagnostic criteria and prognostic factors of this myeloproliferative disease.

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Conflict of interest statement

Competing interests: None.

Figures

Figure 1
Figure 1
Abdominal ultrasound: hepatic nodule, left lobe, 5.5 cm.
Figure 2
Figure 2
Abdominal CT: hepatic nodule, segments 6 to 7, 5.5 cm.
Figure 3
Figure 3
Abdominal magnetic resonance (T1): hepatic nodule, segments 6 to 7, 5.5 cm.
Figure 4
Figure 4
Hepatic nodule histology: islands of hematopoietic elements (EMH).
Figure 5
Figure 5
Bone marrow histology: hypercellularity, megakaryocytic atipia and fibrosis.
See this image and copyright information in PMC

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