Removing ruthenium residues from olefin metathesis reaction products

Abstract

Olefin metathesis has revolutionized the way chemists design and synthesize molecules, mostly due to the development of well-defined ruthenium catalysts with high oxygen-, moisture-, and functional-group tolerance. However, the complete removal of residual ruthenium after the end of a metathesis reaction often imposes significant challenges. This Minireview summarizes the strategies for the sequestration of ruthenium impurities from olefin metathesis post-reaction mixtures, thus comprising a practical guide for synthetic chemists employing ruthenium-catalyzed metathesis reactions in the synthesis of organic or polymeric materials.