doi: 10.1111/j.1399-0004.1990.tb03579.x.
Association of hypercholesterolemia and apolipoprotein E4 in school children
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- PMID: 2268973
- DOI: 10.1111/j.1399-0004.1990.tb03579.x
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Association of hypercholesterolemia and apolipoprotein E4 in school children
Clin Genet.
1990 Oct.
Abstract
To investigate the association of apolipoprotein (APO) E4 and hypercholesterolemia in children, we studied the APOE phenotypes of 51 school-age children with hypercholesterolemia and of 51 age, sex and obesity index-matched controls with normocholesterolemia by two-dimensional gel electrophoresis APOE4 was present in 21 of 51 hypercholesterolemic children (41.2%), and in nine of 51 control subjects (17.6%). The difference was significant (p less than 0.01). This finding indicates that APOE4 is associated with hypercholesterolemia in children.
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