Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990 Oct;38(4):264-9.
doi: 10.1111/j.1399-0004.1990.tb03579.x.

Association of hypercholesterolemia and apolipoprotein E4 in school children

H Yanagi  1 , Y Shimakura, Y Yamanouchi, Y Watanabe, S Tsuchiya, H Hamaguchi
Affiliations

Association of hypercholesterolemia and apolipoprotein E4 in school children

H Yanagi et al. Clin Genet. 1990 Oct.

Abstract

To investigate the association of apolipoprotein (APO) E4 and hypercholesterolemia in children, we studied the APOE phenotypes of 51 school-age children with hypercholesterolemia and of 51 age, sex and obesity index-matched controls with normocholesterolemia by two-dimensional gel electrophoresis APOE4 was present in 21 of 51 hypercholesterolemic children (41.2%), and in nine of 51 control subjects (17.6%). The difference was significant (p less than 0.01). This finding indicates that APOE4 is associated with hypercholesterolemia in children.

PubMed Disclaimer

Publication types

LinkOut - more resources