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Case Reports
. 2011 Jul 28:2011:bcr0620114328.
doi: 10.1136/bcr.06.2011.4328.

Dilated neonatal cisterna magna and Marfan syndrome

Vimal Vasu  1 , Anne H Child, Neena Modi, Mary Rutherford, Frances Cowan
Affiliations
Case Reports

Dilated neonatal cisterna magna and Marfan syndrome

Vimal Vasu et al. BMJ Case Rep. .

Abstract

The authors report the incidental finding of a dilated cisterna magna with an abnormal configuration to the falx in a newborn infant with Marfan syndrome who was recruited to a research study involving whole body MRI. To our knowledge, dilation of the cisterna magna has not previously been reported in patients with Marfan syndrome. Potential implications for antenatal diagnosis, the ethics of recruiting healthy volunteers for research and directions for future work are discussed.

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Conflict of interest statement

Competing interests None.

Figures

Figure 1
Figure 1
Antenatal ultrasound measurements at 21+2 weeks gestation
Figure 2
Figure 2
Cranial ultrasonography images and MR images
See this image and copyright information in PMC

References

    1. De Paepe A, Devereux RB, Dietz HC, et al. Revised diagnostic criteria for the Marfan syndrome. Am J Med Genet 1996;62:417–26 - PubMed
    1. Knirsch W, Kurtz C, Häffner N, et al. Dural ectasia in children with Marfan syndrome: a prospective, multicenter, patient-control study. Am J Med Genet A 2006;140:775–81 - PubMed
    1. Tamminga P, Jennekens FG, Barth PG, et al. An infant with Marfanoid phenotype and congenital contractures associated with ocular and cardiovascular anomalies, cerebral white matter hypoplasia and spinal axonopathy. Eur J Pediatr 1985;143:228–31 - PubMed
    1. Chu NS. Marfan’s syndrome and epilepsy: report of two cases and review of the literature. Epilepsia 1983;24:49–55 - PubMed
    1. Pyeritz RE. Chapter 160, Marfan syndrome and related disorders. In: Principles and Practice of Medical Genetics. Fifth ed New York: Churchill Livingstone; 2006

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