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Case Reports
. 2011 Jul 28:2011:bcr1220103579.
doi: 10.1136/bcr.12.2010.3579.

NMDA receptor encephalitis--expanding the clinical spectrum

Uma Nath  1 , Naomi Margaret Warren, Husam Ali
Affiliations
Case Reports

NMDA receptor encephalitis--expanding the clinical spectrum

Uma Nath et al. BMJ Case Rep. .

Abstract

A young woman presented with memory problems of subacute onset. Imaging was normal. She was admitted with severe complex partial status epilepticus requiring intensive care support and ventilation. Fits proved difficult to control requiring high dose anticonvulsants. She developed a profound amnesic syndrome. A clinical diagnosis of autoimmune encephalitis was considered and she was treated with intravenous steroids with an excellent cognitive outcome. She continues to have occasional seizures.

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Conflict of interest statement

Competing interests None.

Figures

Figure 1
Figure 1
MRI images of patient with NMDA encephalitis.
See this image and copyright information in PMC

References

    1. Dalmau J, Tüzün E, Wu HY, et al. Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma. Ann Neurol 2007;61:25–36 - PMC - PubMed
    1. Dalmau J, Gleichman AJ, Hughes EG, et al. Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol 2008;7:1091–8 - PMC - PubMed
    1. Iizuka T, Sakai F. [Anti-nMDA receptor encephalitis–clinical manifestations and pathophysiology]. Brain Nerve 2008;60:1047–60 - PubMed
    1. Iizuka T, Sakai F, Ide T, et al. Anti-NMDA receptor encephalitis in Japan: long-term outcome without tumor removal. Neurology 2008;70:504–11 - PMC - PubMed
    1. Niehusmann P, Dalmau J, Rudlowski C, et al. Diagnostic value of N-methyl-D-aspartate receptor antibodies in women with new-onset epilepsy. Arch Neurol 2009;66:458–64 - PubMed

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