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Randomized Controlled Trial
. 2012 Sep;46(9):1174-83.
doi: 10.1016/j.jpsychires.2012.05.007. Epub 2012 Jun 12.

Pilot study of treatment for major depression among women prisoners with substance use disorder

Jennifer E Johnson  1 , Caron Zlotnick
Affiliations
Randomized Controlled Trial

Pilot study of treatment for major depression among women prisoners with substance use disorder

Jennifer E Johnson et al. J Psychiatr Res. 2012 Sep.

Abstract

This study, the largest randomized controlled trial of treatment for major depressive disorder (MDD) in an incarcerated population to date, wave-randomized 38 incarcerated women (6 waves) with MDD who were attending prison substance use treatment to adjunctive group interpersonal psychotherapy (IPT) for MDD or to an attention-matched control condition. Intent-to-treat analyses found that IPT participants had significantly lower depressive symptoms at the end of 8 weeks of in-prison treatment than did control participants. Control participants improved later, after prison release. IPT's rapid effect on MDD within prison may reduce serious in-prison consequences of MDD.

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