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Review
. 2012 Nov;16(6):582-6.
doi: 10.1016/j.ejpn.2012.05.004. Epub 2012 Jun 12.

Management of epilepsy associated with tuberous sclerosis complex (TSC): clinical recommendations

Paolo Curatolo  1 , Sergiusz Jóźwiak, Rima Nabbout; TSC Consensus Meeting for SEGA and Epilepsy Management
Collaborators, Affiliations
Review

Management of epilepsy associated with tuberous sclerosis complex (TSC): clinical recommendations

Paolo Curatolo et al. Eur J Paediatr Neurol. 2012 Nov.

Abstract

Tuberous sclerosis complex (TSC) is a leading genetic cause of epilepsy. TSC-associated epilepsy generally begins during the first year of life, and is associated with neurodevelopmental and cognitive problems. Management is challenging and seizures tend to persist in a large proportion of patients despite pharmacological and surgical treatment. This report summarizes the clinical recommendations for the management of TSC-associated epilepsy made by a panel of European experts in March 2012. Current treatment options and outstanding questions are outlined.

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