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Comment
. 2012 Jun 14;12(7):450-1.
doi: 10.1038/nrc3303.

Prostate cancer. Mutational consequences

Comment

Prostate cancer. Mutational consequences

Sarah Seton-Rogers. Nat Rev Cancer. .

Abstract

Two papers have investigated the role of somatic mutations in prostate cancer and have looked more closely at the functional consequences of some of the most common alterations.

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Comment on

  • Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer.
    Barbieri CE, Baca SC, Lawrence MS, Demichelis F, Blattner M, Theurillat JP, White TA, Stojanov P, Van Allen E, Stransky N, Nickerson E, Chae SS, Boysen G, Auclair D, Onofrio RC, Park K, Kitabayashi N, MacDonald TY, Sheikh K, Vuong T, Guiducci C, Cibulskis K, Sivachenko A, Carter SL, Saksena G, Voet D, Hussain WM, Ramos AH, Winckler W, Redman MC, Ardlie K, Tewari AK, Mosquera JM, Rupp N, Wild PJ, Moch H, Morrissey C, Nelson PS, Kantoff PW, Gabriel SB, Golub TR, Meyerson M, Lander ES, Getz G, Rubin MA, Garraway LA. Barbieri CE, et al. Nat Genet. 2012 May 20;44(6):685-9. doi: 10.1038/ng.2279. Nat Genet. 2012. PMID: 22610119 Free PMC article.

References

    1. Nat Genet. 2012 May 20;44(6):685-9 - PubMed
    1. Nature. 2012 Jul 12;487(7406):239-43 - PubMed

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