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Comment
. 2012 Jun 12;21(6):717-9.
doi: 10.1016/j.ccr.2012.05.030.

Rolling the dice to discover the role of DICER in tumorigenesis

Veronica Davalos  1 , Manel Esteller
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Rolling the dice to discover the role of DICER in tumorigenesis

Veronica Davalos et al. Cancer Cell. .
Free article

Abstract

In an effort to identify the consequences of complete DICER1 loss in tumorigenesis, in this issue of Cancer Cell, Ravi et al. characterize the effects of homozygous deletion of Dicer1. Using an in vivo mouse model, they show that genetic deletion of Dicer1 does not preclude tumor formation.

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