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Review
. 2012 Jun;4(2):85-7.
doi: 10.1038/ijos.2012.26.

Bioinformatics advances in saliva diagnostics

Ji-Ye Ai  1 , Barry Smith, David T W Wong
Affiliations
Review

Bioinformatics advances in saliva diagnostics

Ji-Ye Ai et al. Int J Oral Sci. 2012 Jun.

Abstract

There is a need recognized by the National Institute of Dental & Craniofacial Research and the National Cancer Institute to advance basic, translational and clinical saliva research. The goal of the Salivaomics Knowledge Base (SKB) is to create a data management system and web resource constructed to support human salivaomics research. To maximize the utility of the SKB for retrieval,integration and analysis of data, we have developed the Saliva Ontology and SDxMart. This article reviews the informatics advances in saliva diagnostics made possible by the Saliva Ontology and SDxMart.

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Figures

Figure 1
Figure 1
A fragment of the basic Saliva Ontology in its current form.
See this image and copyright information in PMC

References

    1. Garcia I. NIDCR's 2009–2013 strategic plan. J Dent Hyg. 2009;83 4:153–154. - PubMed
    1. Phillips C. Rinse and spit: saliva as a cancer biomarker source. NCI Cancer Bull. 2006;2:39.
    1. NIH . FY 2006 NIH Annual Performance Report/FY 2008 NIH Performance Plan. Bethesda; NIH; p. 2008.p. 82.
    1. Hu S, Li Y, Wang J, et al. Human saliva proteome and transcriptome. J Dent Res. 2006;85 12:1129–1133. - PMC - PubMed
    1. Huang CM, Zhu W. Profiling human saliva endogenous peptidome via a high throughput MALDI–TOF–TOF mass spectrometry. Comb Chem High Throughput Screen. 2009;12 5:521–531. - PubMed

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