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Comment
. 2012 Jun 15;336(6087):1391-2.
doi: 10.1126/science.1224272.

Molecular biology. All packed up and ready to go

Yannick Jacob  1 , Rob Martienssen
Affiliations
Comment

Molecular biology. All packed up and ready to go

Yannick Jacob et al. Science. .

Abstract

Gene silencing depends on the higher-order structure of heterochromatin as well as repressive biochemical modifications.

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Figures

Figure
Figure. Heterochromatin condensation
AtMORC1 and AtMORC6 function similarly in heterochromatin condensation, and both colocalize to the same regions in the nucleus, which suggests that they are in the same pathway and may interact. Recombinant AtMORC6 protein interacts with DMS3, an integral part of the DDR complex. The DDR complex protein DRD1 also regulates chromatin compaction with Pol V independently of their role in RNA-directed DNA methylation.
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References

    1. Moissiard G, et al. Science. 2012;336:1448. 10.1126/science.1221472. - PMC - PubMed
    1. Qian W, et al. Science. 2012;336:1445. - PMC - PubMed
    1. Fraser P, Bickmore W. Nature. 2007;447:413. - PubMed
    1. Rigal M, Mathieu O. Biochim Biophys Acta. 2011;1809:452. - PubMed
    1. Feng S, Jacobsen SE. Curr Opin Plant Biol. 2011;14:179. - PMC - PubMed

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