Lymphocyte choriomeningitis virus plays hide-and-seek with type 1 interferon
- PMID: 22704613
- DOI: 10.1016/j.chom.2012.05.007
Lymphocyte choriomeningitis virus plays hide-and-seek with type 1 interferon
Abstract
In this issue, Macal et al. (2012); Walsh et al. (2012), and Wang et al. (2012) examine how adaptive immune responses to acute and chronic lymphocyte choriomeningitis virus infection are regulated by type 1 interferon produced early during infection by different cell types upon activation by intracellular nucleic acid sensors.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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Plasmacytoid dendritic cells are productively infected and activated through TLR-7 early after arenavirus infection.Cell Host Microbe. 2012 Jun 14;11(6):617-30. doi: 10.1016/j.chom.2012.04.017. Cell Host Microbe. 2012. PMID: 22704622 Free PMC article.
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Timing and magnitude of type I interferon responses by distinct sensors impact CD8 T cell exhaustion and chronic viral infection.Cell Host Microbe. 2012 Jun 14;11(6):631-42. doi: 10.1016/j.chom.2012.05.003. Cell Host Microbe. 2012. PMID: 22704623 Free PMC article.
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Toll-like receptor 7 is required for effective adaptive immune responses that prevent persistent virus infection.Cell Host Microbe. 2012 Jun 14;11(6):643-53. doi: 10.1016/j.chom.2012.04.016. Cell Host Microbe. 2012. PMID: 22704624 Free PMC article.
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