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Review
. 2012 Nov;157(11):2047-57.
doi: 10.1007/s00705-012-1377-9. Epub 2012 Jun 17.

An overview of infectious bursal disease

Hebata Allah Mahgoub  1 , Michael Bailey, Pete Kaiser
Affiliations
Review

An overview of infectious bursal disease

Hebata Allah Mahgoub et al. Arch Virol. 2012 Nov.

Erratum in

  • Arch Virol. 2012 Nov;157(11):2059. Bailey, Michael [added]; Kaiser, Pete [added]

Abstract

Infectious bursal disease (IBD) is a viral immunosuppressive disease of chickens attacking mainly an important lymphoid organ in birds [the bursa of Fabricius (BF)]. The emergence of new variant strains of the causative agent [infectious bursal disease virus (IBDV)] has made it more urgent to develop new vaccination strategies against IBD. One of these strategies is the use of recombinant vaccines (DNA and viral-vectored vaccines). Several studies have investigated the host immune response towards IBDV. This review will present a detailed background on the disease and its causative agent, accompanied by a summary of the most recent findings regarding the host immune response to IBDV infection and the use of recombinant vaccines against IBD.

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